Fractional Excretion of Urea is more sensitive, specific and less affected by the use of diuretics therapy. Fractional Excretion of Urea (FEUrea) = (sCr * uUrea) / (sUrea * uCr) * 100
How to Calculate Fractional Excretion Urea (FEUrea) in Percent
|Serum Creatinine (sCr):||mg/dL|
|Urine Creatinine (uUrea):||mg/dL|
|Serum Urea/BUN (sUrea):||mg/dL|
|Urine Creatinine (uCr):||mg/dL|
|Fractional Excretion of Urea (FEUrea):||%|
A FEUrea less than 35% indicates prerenal failure, while a FEUrea > 35% is indicative of intrinsic renal disease.
Ishir Bhan, MD MPH. “Nephromatic: Fractional Excretion”(04 June, 2012)
Carvounis CP, Nisar S, Guro-Razuman S. “Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure.”. Kidney Int. 2002 Dec;62(6):2223-9. PubMed PMID: 12427149.