Fractional Excretion Urea (FEUrea)

Fractional Excretion of Urea is more sensitive, specific and less affected by the use of diuretics therapy. Fractional Excretion of Urea (FEUrea) = (sCr * uUrea) / (sUrea * uCr) * 100

How to Calculate Fractional Excretion Urea (FEUrea) in Percent

Serum Creatinine (sCr): mg/dL
Urine Creatinine (uUrea): mg/dL
Serum Urea/BUN (sUrea): mg/dL
Urine Creatinine (uCr): mg/dL
Fractional Excretion of Urea (FEUrea): %

A FEUrea less than 35% indicates prerenal failure, while a FEUrea > 35% is indicative of intrinsic renal disease.

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Fractional Excretion Urea (FEUrea) Calculation

References:

Ishir Bhan, MD MPH. “Nephromatic: Fractional Excretion”(04 June, 2012)

Carvounis CP, Nisar S, Guro-Razuman S. “Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure.”. Kidney Int. 2002 Dec;62(6):2223-9.  PubMed PMID: 12427149.

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